4. Nucleotide Metabolism
4.2 Pyrimidine metabolism [MAP:00240]
*b0060 polB, dina; DNA polymerase II (pol II). [EC:2.7.7.7] [SP:DPO2_ECOLI]
*b0184 dnaE, polc; DNA polymerase III, alpha chain. [EC:2.7.7.7] [SP:DP3A_ECOLI]
*b0215 dnaQ, mutd; DNA polymerase III, epsilon chain. [EC:2.7.7.7]
[SP:DP3E_ECOLI]
b0337 codA; cytosine deaminase. [EC:3.5.4.1] [SP:CODA_ECOLI]
*b0470 dnaX, dnaz; DNA polymerase III subunits gamma and tau. [EC:2.7.7.7]
[SP:DP3X_ECOLI]
*b0480 ushA; UDP-sugar hydrolase precursor (UDP-sugar diphosphatase) (UDP-
sugar pyrophosphatase) (5'-nucleotidase ). [EC:3.1.3.5 3.6.1.45]
[SP:USHA_ECOLI]
*b0640 holA; DNA polymerase III, delta subunit. [EC:2.7.7.7] [SP:HOLA_ECOLI]
b0888 trxB; thioredoxin reductase. [EC:1.6.4.5] [SP:TRXB_ECOLI]
b0910 cmk, mssA; cytidylate kinase (CK) (cytidine monophosphate kinase) (CMP
kinase) (mssa protein) (P25). [EC:2.7.4.14] [SP:KCY_ECOLI]
b0945 pyrD; dihydroorotate dehydrogenase (dihydroorotate oxidase)
(dhodehase). [EC:1.3.3.1] [SP:PYRD_ECOLI]
b1062 pyrC; dihydroorotase (DHOase). [EC:3.5.2.3] [SP:PYRC_ECOLI]
b1098 tmk; thymidylate kinase (dTMP kinase). [EC:2.7.4.9] [SP:KTHY_ECOLI]
*b1099 holB; DNA polymerase III, delta' subunit. [EC:2.7.7.7] [SP:HOLB_ECOLI]
b1238 tdk; thymidine kinase. [EC:2.7.1.21] [SP:KITH_ECOLI]
b1281 pyrF; orotidine 5'-phosphate decarboxylase (OMP decarboxylase).
[EC:4.1.1.23] [SP:DCOP_ECOLI]
*b1838 prpA; serine/threonine protein phosphatase prpa. [EC:3.1.3.16]
[SP:PRPA_ECOLI]
*b1842 holE; DNA polymerase III, theta subunit. [EC:2.7.7.7] [SP:HOLE_ECOLI]
b2065 dcd, dus, paxA; deoxycytidine triphosphate deaminase (dCTP deaminase).
[EC:3.5.4.13] [SP:DCD_ECOLI]
b2066 udk; uridine kinase [EC:2.7.1.48]
b2143 cdd; cytidine deaminase (cytidine aminohydrolase) (CDA). [EC:3.5.4.5]
[SP:CDD_ECOLI]
*b2234 nrdA, dnaf; ribonucleoside-diphosphate reductase 1 alpha chain
(ribonucleotide reductase 1) (b1 protein) (r1 protein). [EC:1.17.4.1]
[SP:RIR1_ECOLI]
*b2235 nrdB, ftsb; ribonucleoside-diphosphate reductase 1 beta chain
(ribonucleotide reductase 1) (b2 protein) (r2 protein). [EC:1.17.4.1]
[SP:RIR2_ECOLI]
b2318 truA, hist, asuc, leuk; pseudouridylate synthase I (pseudouridine
synthase I) (uracil hydrolyase). [EC:4.2.1.70] [SP:TRUA_ECOLI]
b2498 upp; uracil phosphoribosyltransferase [EC:2.4.2.9]
*b2518 ndk; nucleoside diphosphate kinase (NDK) (ndp kinase). [EC:2.7.4.6]
[SP:NDK_ECOLI]
*b2675 nrdE; ribonucleoside-diphosphate reductase 2 alpha chain
(ribonucleotide reductase 2) (r1e protein). [EC:1.17.4.1] [SP:RIR3_ECOLI]
*b2676 nrdF; ribonucleoside-diphosphate reductase 2 beta chain (ribonucleotide
reductase 2) (r2f protein). [EC:1.17.4.1] [SP:RIR4_ECOLI]
b2780 pyrG; CTP synthase (UTP--ammonia ligase) (CTP synthetase). [EC:6.3.4.2]
[SP:PYRG_ECOLI]
*b2827 thyA; thymidylate synthase (TS). [EC:2.1.1.45] [SP:TYSY_ECOLI]
*b3164 pnp; polynucleotide phosphorylase [EC:2.7.7.8]
*b3295 rpoA, pez, phs, sez; DNA-directed RNA polymerase alpha chain
(transcriptase alpha chain) (RNA polymerase alpha subunit). [EC:2.7.7.6]
[SP:RPOA_ECOLI]
*b3461 rpoH, htpr, hin, fam; RNA polymerase sigma-32 factor (heat shock
regulatory protein f33.4). [EC:2.7.7.6] [SP:RP32_ECOLI]
b3640 dut, dnaS, sof; deoxyuridine 5'-triphosphate nucleotidohydrolase
(DUTPase) (dutp pyrophosphatase). [EC:3.6.1.23] [SP:DUT_ECOLI]
b3642 pyrE; orotate phosphoribosyltransferase (OPRT) (OPRTase). [EC:2.4.2.10]
[SP:PYRE_ECOLI]
*b3649 rpoZ; DNA-directed RNA polymerase omega chain (transcriptase omega
chain) (RNA polymerase omega subunit). [EC:2.7.7.6] [SP:RPOZ_ECOLI]
*b3701 dnaN; DNA polymerase III, beta chain. [EC:2.7.7.7] [SP:DP3B_ECOLI]
b3831 UDP; uridine phosphorylase (UDRPase). [EC:2.4.2.3] [SP:UDP_ECOLI]
*b3863 polA, resa; DNA polymerase I (POL I). [EC:2.7.7.7] [SP:DPO1_ECOLI]
*b3987 rpoB, gron, nitb, rif, ron, stl, stv, tabd; DNA-directed RNA polymerase
beta chain (transcriptase beta chain) (RNA polymerase beta subunit).
[EC:2.7.7.6] [SP:RPOB_ECOLI]
*b3988 rpoC, tabb; DNA-directed RNA polymerase beta' chain (transcriptase
beta' chain) (RNA polymerase beta' subunit). [EC:2.7.7.6] [SP:RPOC_ECOLI]
*b4213 cpdB; 2',3'-cyclic-nucleotide 2'-phosphodiesterase precursor.
[EC:3.1.4.16] [SP:CN16_ECOLI]
*b4238 nrdD; anaerobic ribonucleoside-triphosphate reductase. [EC:1.17.4.2]
[SP:NRDD_ECOLI]
*b4244 pyrI; aspartate carbamoyltransferase regulatory chain. [EC:2.1.3.2]
[SP:PYRI_ECOLI]
*b4245 pyrB; aspartate carbamoyltransferase catalytic chain (aspartate
transcarbamylase) (ATCase). [EC:2.1.3.2] [SP:PYRB_ECOLI]
*b4259 holC; DNA polymerase III, chi subunit. [EC:2.7.7.7] [SP:HOLC_ECOLI]
*b4372 holD; DNA polymerase III, psi subunit. [EC:2.7.7.7] [SP:HOLD_ECOLI]
*b4382 deoA, tpp, ttg; thymidine phosphorylase (TDRPase). [EC:2.4.2.4]
[SP:TYPH_ECOLI]
*b4384 deoD, pup; purine nucleoside phosphorylase (inosine phosphorylase)
(PNP). [EC:2.4.2.1] [SP:DEOD_ECOLI]