ENTRY       EC 1.1.1.231
NAME        15-Hydroxyprostaglandin-I dehydrogenase (NADP+)
CLASS       Oxidoreductases
            Acting on the CH-OH group of donors
            With NAD+ or NADP+ as acceptor
SYSNAME     (5Z,13E)-(15S)-6,9alpha-Epoxy-11alpha,15-dihydroxyprosta-5,13-
            $dienoate:NADP+ 15-oxidoreductase
REACTION    (5Z,13E)-(15S)-6,9alpha-Epoxy-11alpha,15-dihydroxyprosta-5,13-
            $dienoate + NADP+ =
            (5Z,13E)-6,9alpha-Epoxy-11alpha-hydroxy-15-oxoprosta-5,13-
            $dienoate + NADPH
SUBSTRATE   (5Z,13E)-(15S)-6,9alpha-Epoxy-11alpha,15-dihydroxyprosta-5,13-
            $dienoate
            NADP+
            Prostaglandin I2
PRODUCT     (5Z,13E)-6,9alpha-Epoxy-11alpha-hydroxy-15-oxoprosta-5,13-
            $dienoate
            NADPH
COMMENT     Specific for prostaglandin I2.
DBLINKS     University of Geneva ENZYME DATA BANK: 1.1.1.231
            WIT (What Is There) Metabolic Reconstruction: 1.1.1.231
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