Pyruvate/Oxoglutarate Oxidoreductases

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EC	Enzyme complex	Substrates			Products
1.2.1.51	Pyruvate dehydrogenase	Pyruvate	CoA	NADP+	Acetyl-CoA	CO2	NADPH
1.2.7.1	Pyruvate oxidoreductase	Pyruvate	CoA	Oxidized ferredoxin	Acetyl-CoA	CO2	Reduced ferredoxin
1.2.7.3	2-Oxoglutarate oxidoreductase	2-Oxoglutarate	CoA	Oxidized ferredoxin	Succinyl-CoA	CO2	Reduced ferredoxin

Pyruvate dehydrogenase complex [EC:1.2.1.51]

Organism E1.2.1.51
Pyruvate dehydrogenase
E1 E2 E3
eco [ P | G | T ] b0114(aceE) b0115(aceF) b0116(lpdA)
b3962
hin [ P | G | T ] HI1233 HI1232 HI1231
rpr [ P | G | T ] RP261 RP262 RP530 RP460
RP805
mtu [ P | G | T ] Rv2241
bsu [ P | G | T ] pdhA pdhB pdhC pdhD
bsu [ P | G | T ] acoA acoB acoC acoL
bsu [ P | G | T ] bfmBAA bfmBAB bfmBB yqiV
mge [ P | G | T ] MG274 MG273 MG272 MG271
mpn [ P | G | T ] F11_orf358a F11_orf327 F11_orf402 F11_orf457
mtu [ P | G | T ] Rv2497c Rv2496c Rv2495c Rv0462
Rv2713
Rv3303c
ctr [ P | G | T ] CT245 CT246 CT247 CT557
cpn [ P | G | T ] CPn0304 CPn0305 CPn0306 CPn0833
syn [ P | G | T ] slr1934 sll1721 sll1841 slr1096
ape [ P | G | T ] APE1677 APE1674 APE1671 APE1699
sce [ P | G | T ] YER178W YBR221C YNL071W YFL018C

Organism	E1.2.1.51
Pyruvate dehydrogenase
E1	E2	E3
eco [ P \| G \| T ]	b0114(aceE)	b0115(aceF)	b0116(lpdA) b3962
hin [ P \| G \| T ]	HI1233	HI1232	HI1231
rpr [ P \| G \| T ]	RP261	RP262	RP530	RP460 RP805
mtu [ P \| G \| T ]	Rv2241
bsu [ P \| G \| T ]	pdhA	pdhB	pdhC	pdhD
bsu [ P \| G \| T ]	acoA	acoB	acoC	acoL
bsu [ P \| G \| T ]	bfmBAA	bfmBAB	bfmBB	yqiV
mge [ P \| G \| T ]	MG274	MG273	MG272	MG271
mpn [ P \| G \| T ]	F11_orf358a	F11_orf327	F11_orf402	F11_orf457
mtu [ P \| G \| T ]	Rv2497c	Rv2496c	Rv2495c	Rv0462 Rv2713 Rv3303c
ctr [ P \| G \| T ]	CT245	CT246	CT247	CT557
cpn [ P \| G \| T ]	CPn0304	CPn0305	CPn0306	CPn0833
syn [ P \| G \| T ]	slr1934	sll1721	sll1841	slr1096
ape [ P \| G \| T ]	APE1677	APE1674	APE1671	APE1699
sce [ P \| G \| T ]	YER178W	YBR221C	YNL071W	YFL018C

Pyruvate oxidoreductase (POR) [EC:1.2.7.1]
2-Oxoglutarate oxidoreductase (KOR) [EC:1.2.7.3]

Organism E1.2.7.1
Pyruvate:ferredoxin oxidoreductase
alpha beta gamma delta
eco [ P | G | T ] b1378
tpa [ P | G | T ] TP0939
syn [ P | G | T ] sll0741
hpy [ P | G | T ] HP1110 HP1111 HP1108 HP1109
hpj [ P | G | T ] jhp1037 jhp1038 jhp1035 jhp1036
aae [ P | G | T ] aq_1167 aq_1168 aq_1169 aq_1171a
aae [ P | G | T ] aq_1195 aq_1196 aq_1200 aq_1192a
tma [ P | G | T ] TM0017 TM0018 TM0015 TM0016
mja [ P | G | T ] MJ0267 MJ0266 MJ0269 MJ0268
MJ0264
MJ0265
mth [ P | G | T ] MTH1739 MTH1738 MTH1740
afu [ P | G | T ] AF1701 AF1702 AF1699 AF1700
afu [ P | G | T ] AF2053 AF2052 AF2055 AF2054
pho [ P | G | T ] PH0680
PH0684 PH0681
PH0685 PH0678 PH0679
PH0682
pab [ P | G | T ] PAB1472
PAB1475 PAB1473
PAB1476 PAB1470 PAB1471
PAB1474
E1.2.7.3
2-Oxoglutarate:ferredoxin oxidoreductase
alpha beta gamma delta
mtu [ P | G | T ] Rv2455c Rv2454c Rv2455c
hpy [ P | G | T ] HP0589 HP0590 HP0591 HP0588
hpj [ P | G | T ] jhp0537 jhp0538 jhp0539 jhp0536
tma [ P | G | T ] TM0878 TM0405 TM0406
tma [ P | G | T ] TM1164 TM1165
mja [ P | G | T ] MJ0276 MJ0537 MJ0536 MJ0146
mth [ P | G | T ] MTH1033 MTH1034 MTH1035 MTH1032
mth [ P | G | T ] MTH536 MTH537
afu [ P | G | T ] AF0469 AF0468 AF0471 AF0470
afu [ P | G | T ] AF0749 AF0750 AF0749
pho [ P | G | T ] PH1662
PH1666 PH1661
PH1665 PH1660
PH1663
pab [ P | G | T ] PAB2359
PAB0346 PAB0344
PAB0347 PAB0345
PAB0348 PAB0341
ape [ P | G | T ] APE1473 APE1472
ape [ P | G | T ] APE2126 APE2128
E1.2.7.-
2-Oxoisovalerate:ferredoxin oxidoreductase
alpha beta gamma delta
tma [ P | G | T ] TM1759 TM1758
mth [ P | G | T ] MTH704 MTH705 MTH703
E1.2.7.-
Indolepyruvate:ferredoxin oxidoreductase
alpha beta gamma delta
mth [ P | G | T ] MTH1852 MTH1853 MTH854
afu [ P | G | T ] AF1489 AF2030
pho [ P | G | T ] PH1138 PH0229
pho [ P | G | T ] PH0765 PH0764
pab [ P | G | T ] PAB0718 PAB0143
pab [ P | G | T ] PAB0855 PAB0857

Organism	E1.2.7.1
Pyruvate:ferredoxin oxidoreductase
alpha	beta	gamma	delta
eco [ P \| G \| T ]	b1378
tpa [ P \| G \| T ]	TP0939
syn [ P \| G \| T ]	sll0741
hpy [ P \| G \| T ]	HP1110	HP1111	HP1108	HP1109
hpj [ P \| G \| T ]	jhp1037	jhp1038	jhp1035	jhp1036
aae [ P \| G \| T ]	aq_1167	aq_1168	aq_1169	aq_1171a
aae [ P \| G \| T ]	aq_1195	aq_1196	aq_1200	aq_1192a
tma [ P \| G \| T ]	TM0017	TM0018	TM0015	TM0016
mja [ P \| G \| T ]	MJ0267	MJ0266	MJ0269	MJ0268 MJ0264 MJ0265
mth [ P \| G \| T ]	MTH1739	MTH1738	MTH1740
afu [ P \| G \| T ]	AF1701	AF1702	AF1699	AF1700
afu [ P \| G \| T ]	AF2053	AF2052	AF2055	AF2054
pho [ P \| G \| T ]	PH0680 PH0684	PH0681 PH0685	PH0678	PH0679 PH0682
pab [ P \| G \| T ]	PAB1472 PAB1475	PAB1473 PAB1476	PAB1470	PAB1471 PAB1474
	E1.2.7.3
2-Oxoglutarate:ferredoxin oxidoreductase
alpha	beta	gamma	delta
mtu [ P \| G \| T ]	Rv2455c	Rv2454c	Rv2455c
hpy [ P \| G \| T ]	HP0589	HP0590	HP0591	HP0588
hpj [ P \| G \| T ]	jhp0537	jhp0538	jhp0539	jhp0536
tma [ P \| G \| T ]	TM0878	TM0405	TM0406
tma [ P \| G \| T ]	TM1164	TM1165
mja [ P \| G \| T ]	MJ0276	MJ0537	MJ0536	MJ0146
mth [ P \| G \| T ]	MTH1033	MTH1034	MTH1035	MTH1032
mth [ P \| G \| T ]	MTH536	MTH537
afu [ P \| G \| T ]	AF0469	AF0468	AF0471	AF0470
afu [ P \| G \| T ]	AF0749	AF0750	AF0749
pho [ P \| G \| T ]	PH1662 PH1666	PH1661 PH1665	PH1660 PH1663
pab [ P \| G \| T ]	PAB2359 PAB0346	PAB0344 PAB0347	PAB0345 PAB0348	PAB0341
ape [ P \| G \| T ]	APE1473	APE1472
ape [ P \| G \| T ]	APE2126	APE2128
	E1.2.7.-
2-Oxoisovalerate:ferredoxin oxidoreductase
alpha	beta	gamma	delta
tma [ P \| G \| T ]	TM1759			TM1758
mth [ P \| G \| T ]	MTH704	MTH705	MTH703
	E1.2.7.-
Indolepyruvate:ferredoxin oxidoreductase
alpha	beta	gamma	delta
mth [ P \| G \| T ]	MTH1852	MTH1853	MTH854
afu [ P \| G \| T ]	AF1489	AF2030
pho [ P \| G \| T ]	PH1138	PH0229
pho [ P \| G \| T ]	PH0765	PH0764
pab [ P \| G \| T ]	PAB0718	PAB0143
pab [ P \| G \| T ]	PAB0855	PAB0857

Last updated: October 8, 1999
Compiled by KEGG

Pyruvate/Oxoglutarate Oxidoreductases

Pyruvate dehydrogenase complex [EC:1.2.1.51]

Pyruvate oxidoreductase (POR) [EC:1.2.7.1] 2-Oxoglutarate oxidoreductase (KOR) [EC:1.2.7.3]

Pyruvate oxidoreductase (POR) [EC:1.2.7.1]
2-Oxoglutarate oxidoreductase (KOR) [EC:1.2.7.3]